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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFATC1
All Species:
4.24
Human Site:
S178
Identified Species:
11.67
UniProt:
O95644
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95644
NP_006153.2
943
101243
S178
L
S
P
A
S
S
L
S
S
R
S
C
N
S
E
Chimpanzee
Pan troglodytes
XP_512184
703
76715
Rhesus Macaque
Macaca mulatta
XP_001088054
930
100304
Y180
A
S
S
Y
E
S
N
Y
S
Y
P
Y
A
S
P
Dog
Lupus familis
XP_541045
949
102463
S182
S
S
Y
E
S
N
F
S
Y
P
Y
A
S
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88942
717
77815
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509446
847
89309
D102
G
T
E
S
S
P
P
D
P
G
P
K
I
H
E
Chicken
Gallus gallus
XP_418906
927
102137
Y178
A
S
S
Y
E
S
N
Y
S
Y
P
Y
T
S
P
Frog
Xenopus laevis
NP_001085919
704
78205
Zebra Danio
Brachydanio rerio
NP_001038624
867
94251
L122
G
Y
R
D
P
T
C
L
S
P
A
S
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.1
93.7
75.5
N.A.
67.4
N.A.
N.A.
44.8
74.9
54.7
54.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.7
94.8
82
N.A.
71
N.A.
N.A.
55.4
83.3
62.8
67.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
26.6
20
N.A.
0
N.A.
N.A.
13.3
26.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
26.6
40
N.A.
0
N.A.
N.A.
26.6
26.6
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
12
0
0
0
0
0
0
12
12
12
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
12
23
0
0
0
0
0
0
0
0
0
23
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
23
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% K
% Leu:
12
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
23
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
0
12
12
12
0
12
23
34
0
0
12
23
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
12
45
23
12
34
34
0
23
45
0
12
12
23
34
12
% S
% Thr:
0
12
0
0
0
12
0
0
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
23
0
0
0
23
12
23
12
23
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _